Today while starting Outlook 2010, it was throwing a strange error, soon after the splash screen it showed this error “Cannot start Microsoft Office Outlook. Cannot Open the Outlook Window”. Even after uninstalling and repairing Outlook 2010 using the Office 2010 set up, the same error occurred. Outlook failed to start even the safe mode when this error occurred (Click CTRL to open Outlook in safe mode).

Outlook 2010

This error is due to the problem with Outlook navigation panel which is failing to start and this could be due to many reasons like improper shutdown of Outlook.

Outlook Error

How to fix this issue:

The fix to this problem depends on the issue with Outlook. You can fix this issue using the methods mentioned below.

1. Open Start menu and Click Run (Windows Key + R) and type Outlook.exe /resetnavpane. Now try opening outlook, if the issue was due to navigation panel, resetting it would solve the issue. If the issue is still not solved, try step 2.

2.  Run the Inbox Repair tool in Outlook- Inbox repair tool (Scanpst.exe) is included in the Office CD and is a tool to repair issues with Inbox personal folder (.pst) files. You can check the Microsoft KB article 272227 for more details on this.

It is most likely that you can solve this issue using Step 1.

Thanks to Microsoft answers for the tip.