Earlier we had written on how to customize your Facebook layout with Facebook Expressions Application. Here is another Facebook Application which can give a beautiful look to your profile. This application is similar to Facebook Expressions and it will appear in the sidebar of your profile. You can install these layouts in your Facebook Profile by directly clicking on them (you will need to log in to your Facebook account).
You can check out more layouts at LayoutCodez.
Here is my customized Facebook layout.